Controlling the growth of Escherichia coli by layer-by-layer encapsulation

Escherichia coli is one of the most common commensal aerobic bacteria in gut microbiota humans (and other mammals). Nevertheless, if left free to proliferate, it can induce a large range diseases from diarrhoea extra-intestinal diseases. In recent years, this bacterium had become increasingly resistant antibiotics. It therefore essential implement new approaches able maintain both bacterial viability and control their proliferation. context, we developed process encapsulate polymer shells. We took advantage fact that has negatively charged surface modified via layer-by-layer process, i.e. with oppositely polyelectrolyte pairs (namely chitosan as polycation alginate or dextran sulfate polyanion). successfully demonstrate controlled coating zeta potential measurement, encapsulated delay growth due multilayer coating. This was dependent on number layers.